To determine the factors associated with outcomes in organophosphate and carbamate poisoning.

Authors

  • Rabail Altaf Gambat Medical College, PSAQSJIMS, Gambat.
  • Danish Kumar Goswami LUMHS, Jamshoro.
  • Nargis Pirya Gambat Medical College, PSAQSJIMS, Gambat.
  • Mansoor Ali Gambat Medical College, PSAQSJIMS, Gambat.
  • Abdul Hafeez Abro SMBBMU.
  • Muhammad Shafay HBS Medical and Dental College, Islamabad.
  • Pardeep Kumar PUMHS, Nawab, Shah.

DOI:

https://doi.org/10.29309/TPMJ/2026.33.04.9746

Keywords:

Carbamate Poisoning, Clinical Presentation, Factors, Organophosphate Poisoning, Outcomes, Pre-hospitalization

Abstract

Objective: To determine factors associated with outcomes in organophosphate and carbamate poisoning remain crucial in understanding the clinical management and prevention strategies for these toxic exposures. Study Design: Prospective Observational study. Setting: Gambat Medical College. Period: January to July 2023. Methods: Involved 226 participants with organophosphate and carbamate poisoning. Sample size was calculated based on pre-hospitalization mortality rates. Data collection encompassed demographics, clinical presentation, and pre-hospitalization factors. Results: The majority of participants intended poisoning for suicide (91.0%), with no significant survival difference based on intention or previous suicide history. Age, educational status, and pre-hospital care significantly influenced survival chances. Clinical presentations varied, including vomiting, respiratory issues, and central nervous system toxicity. Conclusion: Factors such as age, educational status, and pre-hospital care significantly influence outcomes in organophosphate and carbamate poisoning. Clinical presentations vary widely, emphasizing the need for individualized management approaches. Understanding these factors is crucial for effective clinical management and preventive measures.

Author Biographies

Rabail Altaf, Gambat Medical College, PSAQSJIMS, Gambat.

MBBS, DMJ, Assistant Professor Forensic Medicine and Toxicology, 

Danish Kumar Goswami, LUMHS, Jamshoro.

MBBS, Resident Physician Internal Medicine, 

Nargis Pirya, Gambat Medical College, PSAQSJIMS, Gambat.

MBBS, M.Phil (Pharmacology), Assistant Professor Pharmacology, 

Mansoor Ali, Gambat Medical College, PSAQSJIMS, Gambat.

MBBS, DMJ, Assistant Professor, Forensic Medicine and Toxicology, 

Abdul Hafeez Abro, SMBBMU.

MBBS, DMJ, Lecturer Forensic Medicine, 

Muhammad Shafay, HBS Medical and Dental College, Islamabad.

MBBS, DMJ, Assistant Professor, 

Pardeep Kumar, PUMHS, Nawab, Shah.

MBBS, DMJ, Associate Professor, 

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Published

2026-03-10

Issue

Section

Origianl Article