Single dose hydrocortisone for optimized wound healing post tooth-extraction in diabetic patients: A randomized clinical trial.

Abstract

Objective: To determine the effectiveness of a single dose corticosteroid injection after tooth extraction among controlled diabetic patients to improve wound healing. Study Design: Randomized Clinical Trial. Setting: Department of Oral and Maxillofacial Surgery, Madinah Teaching Hospital (MTH) Faisalabad. Period: March 01, 2024 to June 30, 2024. Methods: Prior to each patient's tooth extraction, randomization and group assignment was carried out using computer software Research Randomizer. Signed informed consent from each patient was obtained. A total of 85 patients were included in the study. These patients were divided into two groups control group and the group treated with hydrocortisone injection. Wound healing post extraction on the 6^th day was assessed by Landry Healing Index. Data analysis utilized SPSS software and Independent sample t-test was applied for comparison between groups. A significance level of ≤0.05 was used to determine statistical significance. Results: The results obtained were statistically significant as the corticosteroid treated group showed higher Landry healing index score of 2.84 than 2.40 of the control group which indicated the least effective healing. Conclusion: This study concluded that single dose corticosteroid was effective to improve wound healing post extraction in controlled diabetic patients.