Efficacy of tamsolusin hydrochloride as medical expulsive therapy in lower ureteric calculi < 9mm in adults.

Authors

  • Babar Baig Indus Hospital Karachi.
  • Shahid Hussain Soomro Chandka Medical College SMBBMU Larkana.
  • Abdul Sattar Abro Chandka Medical College SMBBMU Larkana.
  • Nadia Bhatti Chandka Medical College SMBBMU Larkana.
  • Vaqar-e-Saher Shah Chandka Medical College SMBBMU Larkana.
  • Ehsan Ullah Malik Chandka Medical College SMBBMU Larkana.

DOI:

https://doi.org/10.29309/TPMJ/2022.29.06.6757

Keywords:

Lower Ureteric Calculi, Tamsolusin, <9 mm

Abstract

Objectives: To determine the efficacy of Tamsolusin Hydrochloride as medical expulsive therapy in removal of lower ureteric calculi < 9 mm in adults. Study Design: Cross-sectional study. Setting: Naz Memorial Hospital Karachi. Period: July 2019 to December 2019. Material & Methods: Using non-probability convenient sampling technique was conducted for 6 months. After ethical approval patients attending outpatient department with complains of bloody urine, abdominal, flank or groin pain and diagnosed as lower ureteric calculi < 9mm on ultrasonography. Upper ureteric or kidney calculi above 9 mm, patients already on Tamsolusin and lost to follow up or not willing to participate were excluded. Time period of the study was 4 weeks. Patients were started on Tamsolusin 0.4 mg once daily for 30 days. SPSS version 23.0 was used for data analysis. Qualitative data was reported as frequency in percentages. Results:  Age range of patients was 18-50 years with mean age of 35.54 ± 10.20 years. 48 (40%) between 6 to 7 mm. After 1 month of follow up, total of 94 (78%) of patients were found to have expulsion of ureteric calculi. From the total of 30 days, the recorded frequency of calculi expulsion was 94 (78%). Among them, 25 (27%) patients were reported to have expulsion of calculi in between 15 to 19 days.32 (34%) patients between 20-24 days, while 37 (39%) patients between 25 to 29 days. Conclusion: Tamsolusin was significantly effective in expulsion of calculi with most calculi reported to be expulsed between 20-29 days of treatment. Patients also reported in significant decrease in pain frequency and were satisfied with treatment with Tamsolusin for lower ureteric calculi < 9mm.

Author Biographies

Babar Baig, Indus Hospital Karachi.

MBBS, FCPS (Urology), Senior Registrar Urology, 

Shahid Hussain Soomro, Chandka Medical College SMBBMU Larkana.

FCPS, Associate Professor Surgery, 

Abdul Sattar Abro, Chandka Medical College SMBBMU Larkana.

MS, Assistant Professor Surgery, 

Nadia Bhatti, Chandka Medical College SMBBMU Larkana.

FCPS, Assistant Professor Surgery, 

Vaqar-e-Saher Shah, Chandka Medical College SMBBMU Larkana.

FCPS, Assistant Professor Surgery, 

Ehsan Ullah Malik, Chandka Medical College SMBBMU Larkana.

FCPS, Assistant Professor Surgery, 

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Published

2022-05-31