Multidrug-resistant urinary tract isolates of escherichia coli: Frequency and patient demographics in a Tertiary Care Hospital.


  • Salman Azhar MTH, UMDC, Faisalabad.
  • Muhmmad Wasif Baig MTH, UMDC, Faisalabad.
  • Shahid Rasool MTH, UMDC, Faisalabad.
  • Rizwan Rasool Khan MTH, UMDC, Faisalabad.
  • Talha Munir MTH, UMDC, Faisalabad.
  • Umber Fatima Allied Hospital, Faisalabad.
  • Muhammad Ahsan University of Faisalabad



Cystitis, E. Coli, Gram Negative, MDR, Muti-drug Resistance, UTI, Urine Infection, Urine Culture


Urinary tract infections (UTIs) are a major burden to the health care as it is estimated that around 150 million UTIs occur yearly worldwide. Enterobacteriaceae are the most common agent causing serious urinary tract infections; and MDR cases are increasing day by day. Objectives: To determine the frequency and patient demographics of multidrug resistant urinary tract isolates of Escherichia Coli in a Tertiary Care Hospital. Study Design: Retrospective cross sectional study. Setting: Medicine Department of Madinah Teaching Hospital / The University of Faisalabad, Faisalabad. Period: From May 2016 to Sep 2018. Material & Methods: 187 patients of age 15 to 90 years with positive E. coli on urine culture and sensitivity were included in this Retrospective cross sectional study. All those patients with history of dysuria (pain during urination) or frequent urination (more than 7 times per day) were advised urine complete analysis and those with >5 WBCs or pus cells /HPF or having positive for leukocyte esterase and/or nitrite, were advised urine culture and sensitivity. Main outcome variable was the frequency of MDRE cases among the culture positive E. coli UTI patients. Results: Among all the cases of E. coli UTI, frequency of MDRE UTI was 66.8% (n=125) and rest 33.2% (n= 62) cases were not MDR UTI. 97.3% patients were resistant to lactam antibiotics, 95.7% were resistant to quinolones and 68.4% were resistant to aminoglycosides.

Author Biographies

Salman Azhar, MTH, UMDC, Faisalabad.

MBBS, FCPS (Medicine)

Assistant Professor of Medicine


Muhmmad Wasif Baig, MTH, UMDC, Faisalabad.

MBBS, FCPS (Nephrology)

Assistant Professor Nephrology


Shahid Rasool, MTH, UMDC, Faisalabad.

MBBS, FCPS (Gastroenterology)

Associate Professor Gastroenterology


Rizwan Rasool Khan, MTH, UMDC, Faisalabad.

MBBS, FCPS (Medicine)

Associate Professor Medicine


Talha Munir, MTH, UMDC, Faisalabad.

MBBS, FCPS (Gynaecology)

Assistant Professor Obstetrics & Gynecology


Umber Fatima, Allied Hospital, Faisalabad.


Medical Officer