Curve decline of COVID-19: An analysis of first wave of disease in Pakistan– A cross-sectional study.

  • Asma Naseer Cheema Children’s Hospital & The Institute of Child Health, Multan.
  • Aneeqa Naz Children’s Hospital and The Institute of Child Health, Multan.
  • Muhammad Younas Combined Military Hospital Multan. National University of Medical Sciences, Rawalpindi.
  • Azra Azra Institute of Basic Medical Sciences (IBMS), Khyber Medical University, Peshawar.
  • Yasmeen Batool Nishtar Medical University, Multan.
  • Syed Zahid Ali Zaidi Children’s Hospital and The Institute of Child Health, Multan.
Keywords: Azithromycin, COVID-19, Paracetamol, Symptomatic

Abstract

Objective: The objective was to observe the COVID-19 rise and fall, disease pattern, clinical presentation, effective treatment and outcome in native population. Study Design: Cross Sectional study. Setting: Children’s Hospital Multan, Nishtar Hospital Multan, CMH Multan and Teaching Hospital of Kohat. Period: March 2020 to August 2020. Material & Methods: A total of 2,186 subjects with the suspicion of COVID-19 were enrolled in this study. Chi-square test was used to see the difference in disease distribution. Results: Of total, 779 patients were found positive for COVID-19, 47.11% were symptomatic. Of all positive subjects, no significant difference of disease spread was observed in young (<40 years) versus old age (>40 years) [X2 = 3.14; P=0.076). There were more asymptomatic female carriers than male (X2 = 11.68; P=0.001). The rise in cases was observed in May-June after maximum exposure on Eid festival then decline in July. Overall mortality rate was 3.98%. Conclusions: The mortality rate was higher in the start, then gradually declined (9.57-0) %. The disease prevalence was higher in male, and in the age group of 21-50 years. The mortality rate was higher in old age group (>40 years). Paracetamol and azithromycin proved to be effective in mild to moderate symptomatic patients.

Author Biographies

Asma Naseer Cheema, Children’s Hospital & The Institute of Child Health, Multan.

MBBS, M.Phi, PhD

Associate Professor Chemical Pathology

Aneeqa Naz, Children’s Hospital and The Institute of Child Health, Multan.

Ph.D

Microbiologist Pathology

Muhammad Younas, Combined Military Hospital Multan. National University of Medical Sciences, Rawalpindi.

FCPS

Assistant Professor Chemical Pathology

Azra Azra, Institute of Basic Medical Sciences (IBMS), Khyber Medical University, Peshawar.

MPhil, Ph.D

Scholar Microbiology

Yasmeen Batool, Nishtar Medical University, Multan.

FCPS

Assistant Professor Haematology

Syed Zahid Ali Zaidi, Children’s Hospital and The Institute of Child Health, Multan.

MD

Medical Officer Pathology

Published
2021-06-10