Association of serum uric acid with systemic blood pressure – A Cross Sectional study.

Authors

  • Shumail Saeed Siddiqui Indus Medical College Tando Muhammad Khan, Sindh, Pakistan.
  • Shagufta Memon Khairpur Medical College, Khairpur Mirs, Sindh, Pakistan.
  • Shumaila Shaikh Khairpur Medical College, Khairpur Mirs, Sindh, Pakistan.
  • Umair Ali Soomro Indus Medical College Tando Muhammad Khan, Sindh, Pakistan.
  • Sadia Tabassum Suleman Roshan Medical College, Tando Adam, Sindh, Pakistan.
  • Kashif Rasheed Shaikh Suleman Roshan Medical College, Tando Adam, Sindh, Pakistan.
  • Haji Khan Khoharo Isra University, Hyderabad, Sindh, Pakistan.

DOI:

https://doi.org/10.29309/TPMJ/2022.29.01.4747

Keywords:

Age, Body Weight, Diastolic BP, Systolic BP, Uric Acid

Abstract

Objective: To determine association of Serum Uric Acid levels (SUA) in subjects suffering Systemic Blood Pressure and to determine its association with systolic and diastolic blood pressure. Study Design: Cross Sectional Study. Setting: Department of Faculty of Medicine and Allied Medical Sciences, Isra University, Hyderabad, Sindh, Pakistan. Period: January 2018 to September 2019. Material & Methods: 150 diagnosed cases of systemic hypertension and 150 controls were selected though non-probability purposive sampling according to inclusion and exclusion criteria. 2 ml venous blood was taken, centrifuged and sera were used for uric acid. Data was saved in a pre- structured Performa. Statistical software (SPSS v 21.0, IBM, Incorporation, USA) of data variables was analyzed at 95% CI (P ≤ 0.05). Results: Serum uric acid in controls was 2.93±0.72 compared to cases 4.25±1.44 mg/dl (P=0.0001). Hyperuricemia was observed in 58 (38.6%) cases compared to 23 (15.3%) controls. Uric acid shows strong positive association with Systolic BP (r= 0.52*, p=0.0001) and Diastolic BP (r= 0.46**, p=0.0001). Conclusion: We found hyperuricemia in 58 (38.6%) of systemic hypertension cases. Systolic and Diastolic Blood pressure show positive association with uric acid.  

Author Biographies

Shumail Saeed Siddiqui, Indus Medical College Tando Muhammad Khan, Sindh, Pakistan.

MBBS, M.Phil

Assistant Professor Pathology

Shagufta Memon, Khairpur Medical College, Khairpur Mirs, Sindh, Pakistan.

MBBS, M.Phil

Assistant Professor Physiology

Shumaila Shaikh, Khairpur Medical College, Khairpur Mirs, Sindh, Pakistan.

MBBS, M.Phil

Assistant Professor Biochemistry

Umair Ali Soomro, Indus Medical College Tando Muhammad Khan, Sindh, Pakistan.

MBBS, M.Phil

Assistant Professor Hematology

Sadia Tabassum, Suleman Roshan Medical College, Tando Adam, Sindh, Pakistan.

MBBS, M.Phil

Assistant Professor Biochemistry

Kashif Rasheed Shaikh, Suleman Roshan Medical College, Tando Adam, Sindh, Pakistan.

MBBS, M.Phil

Associate Professor Pharmacology

Haji Khan Khoharo, Isra University, Hyderabad, Sindh, Pakistan.

MBBS, M.Phil, FCPS

Associate Professor Faculty of Medicine

and Allied Medical Sciences

Downloads

Published

2021-12-31